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CJC-1295 + Ipamorelin: the stack guide

By the Peptide Protocol editorial team · reviewed

CJC-1295 and Ipamorelin are the canonical GHRH + GHRP pair. They produce a larger, more physiological GH pulse together than either does alone, without the cortisol or prolactin spikes that older GHRPs (GHRP-2, GHRP-6) tend to cause.

Best forRecomposition, sleep quality, recovery, anti-aging protocols.
CadenceA common protocol is 100 mcg of each, injected subcutaneously together pre-bed (and optionally a second pulse pre-workout or first-thing-am).
TagsGH axis Recovery

Why CJC-1295 and Ipamorelin pair well

CJC-1295 is a long-acting GHRH analog that raises baseline GH-releasing tone. Ipamorelin is a selective ghrelin receptor agonist that triggers acute GH pulses. Used together, the GHRH increases the amplitude of the GHRP-induced pulse — the result is a stronger, cleaner spike than either compound alone.

Suggested cadence

A common protocol is 100 mcg of each, injected subcutaneously together pre-bed (and optionally a second pulse pre-workout or first-thing-am). Cycles typically run 8–12 weeks with at least a 4-week break, since chronic GHRH stimulation can blunt receptor sensitivity.

This is informational only — dosing should always be individualized and discussed with a qualified clinician.

Reconstitution notes

CJC-1295: A common ratio is 2 ml of bacteriostatic water for a 2 mg vial. Open the CJC-1295 calculator →

Ipamorelin: A common ratio is 2 ml of bacteriostatic water for a 5 mg vial. Open the Ipamorelin calculator →

Side effects to watch for

Mild head rush, flushing, or hunger 10–20 minutes after injection are common and short-lived. Numbness or tingling in the hands (carpal tunnel-like) is the most reported side effect at higher doses; it usually resolves with dose reduction or a short break.

The two compounds

Track this stack on iPhone

Peptide Protocol schedules both compounds, calculates reconstitution, and rotates injection sites automatically.

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Frequently asked questions

Why stack CJC-1295 with Ipamorelin?

CJC-1295 and Ipamorelin are the canonical GHRH + GHRP pair. They produce a larger, more physiological GH pulse together than either does alone, without the cortisol or prolactin spikes that older GHRPs (GHRP-2, GHRP-6) tend to cause.

What is the typical CJC-1295 + Ipamorelin dose?

A common protocol is 100 mcg of each, injected subcutaneously together pre-bed (and optionally a second pulse pre-workout or first-thing-am). Cycles typically run 8–12 weeks with at least a 4-week break, since chronic GHRH stimulation can blunt receptor sensitivity.

Can you inject CJC-1295 and Ipamorelin in the same syringe?

Many users co-administer GHRH + GHRP pairs (like CJC-1295 + Ipamorelin) in a single syringe to reduce injections, since both are stable in bacteriostatic water for short periods. For other pairs, draw and inject separately to minimize compatibility risk and to attribute any reaction to the correct compound.

What side effects should I watch for?

Mild head rush, flushing, or hunger 10–20 minutes after injection are common and short-lived. Numbness or tingling in the hands (carpal tunnel-like) is the most reported side effect at higher doses; it usually resolves with dose reduction or a short break.

How long should a CJC-1295 + Ipamorelin cycle run?

Most user-reported cycles run 4–12 weeks depending on the goal. GH-axis stacks are typically cycled with a break of 4 weeks or more between blocks to preserve receptor sensitivity. Soft-tissue stacks are usually run continuously until the injury resolves.

Educational use only. Peptide Protocol is an informational tool. Nothing on this page constitutes medical advice. Many peptides are prescription-only or restricted in your jurisdiction. Always consult a licensed healthcare professional before injecting any compound.