BPC-157 + GHK-Cu: the stack guide
BPC-157 plus GHK-Cu is a connective-tissue stack: BPC-157 for the deeper structural healing, GHK-Cu for skin, hair, and superficial tissue remodeling. Often used alongside the BPC/TB stack, or after surgery once the wound has closed.
Why BPC-157 and GHK-Cu pair well
BPC-157 drives angiogenesis and fibroblast activity in deeper structures. GHK-Cu (copper peptide) modulates extracellular matrix remodeling, suppresses TGF-β1-driven fibrosis, and improves dermal regeneration. The pairing is favored when both deep tissue and skin/scar quality are concerns.
Suggested cadence
BPC-157 250–500 mcg subcutaneous daily, plus GHK-Cu 1–2 mg subcutaneous daily — frequently injected near the affected area when targeting a specific scar or injury. Topical GHK-Cu serums are also used in parallel for surface-level skin support.
This is informational only — dosing should always be individualized and discussed with a qualified clinician.
Reconstitution notes
BPC-157: A common ratio is 2 ml of bacteriostatic water for a 5 mg vial. Open the BPC-157 calculator →
GHK-Cu: A common ratio is 5 ml of bacteriostatic water for a 50 mg vial. Open the GHK-Cu calculator →
Side effects to watch for
GHK-Cu can cause a metallic taste and brief blue-green discoloration at the injection site (the copper). Dose-related drops in blood pressure have been reported at higher doses. Avoid stacking with other copper-containing supplements.
The two compounds
Track this stack on iPhone
Peptide Protocol schedules both compounds, calculates reconstitution, and rotates injection sites automatically.
See the app →Frequently asked questions
Why stack BPC-157 with GHK-Cu?
BPC-157 plus GHK-Cu is a connective-tissue stack: BPC-157 for the deeper structural healing, GHK-Cu for skin, hair, and superficial tissue remodeling. Often used alongside the BPC/TB stack, or after surgery once the wound has closed.
What is the typical BPC-157 + GHK-Cu dose?
BPC-157 250–500 mcg subcutaneous daily, plus GHK-Cu 1–2 mg subcutaneous daily — frequently injected near the affected area when targeting a specific scar or injury. Topical GHK-Cu serums are also used in parallel for surface-level skin support.
Can you inject BPC-157 and GHK-Cu in the same syringe?
Many users co-administer GHRH + GHRP pairs (like CJC-1295 + Ipamorelin) in a single syringe to reduce injections, since both are stable in bacteriostatic water for short periods. For other pairs, draw and inject separately to minimize compatibility risk and to attribute any reaction to the correct compound.
What side effects should I watch for?
GHK-Cu can cause a metallic taste and brief blue-green discoloration at the injection site (the copper). Dose-related drops in blood pressure have been reported at higher doses. Avoid stacking with other copper-containing supplements.
How long should a BPC-157 + GHK-Cu cycle run?
Most user-reported cycles run 4–12 weeks depending on the goal. GH-axis stacks are typically cycled with a break of 4 weeks or more between blocks to preserve receptor sensitivity. Soft-tissue stacks are usually run continuously until the injury resolves.
Educational use only. Peptide Protocol is an informational tool. Nothing on this page constitutes medical advice. Many peptides are prescription-only or restricted in your jurisdiction. Always consult a licensed healthcare professional before injecting any compound.